Vaccines against melanoma

https://www.abc.net.au/news/2022-12-15/world-first-melanoma-vaccine-may-be-the-penicillin-moment/101773886

Results of an early trial by Biotech company Moderna indicate the personalised treatment reduces the risk of recurrence or death from melanoma by 44 per cent, compared with results from its immunotherapy drug alone.

The vaccine calls on the same technology used in certain mRNA COVID vaccines, and relies on the vaccine being administered in conjunction with Moderna's immunotherapy drug, Keytruda.

The trial is the first to make use of personalised vaccines in cancer treatment, and to show that combining mRNA technology with Keytruda delivers better results for melanoma patients — and possibly patients with other cancers too.

Professor Georgina Long of the Melanoma Institute of Australia said while a much larger trial would be run next year, early results were promising.


Georgina Long believes it is a key breakthrough. (ABC News: Shaun Kingma)
"It may be the penicillin moment in cancer therapy," Professor Long said.

"It is possible to see that (patients) may have cancer as a long-term disease rather than a death sentence," she said.

Melanoma is Australia's most deadly skin cancer. More than 17,000 people will be diagnosed with the condition this year, and nearly 1,300 people are expected to die from the disease.

How it works

The aim of combining a vaccine with immunotherapy is to target and kill cancerous cells so that recurrence is delayed or prevented.

While immunotherapy stimulates the body's immune system to find and fight cancerous cells, mRNA vaccine technology can be tailored to target the specific mutation in a patient's tumour.

Personalised vaccines make use of genetic sequencing to identify unique mutations in the cells of the patient's tumour.

The mRNA vaccine is then formulated to prompt the patient's immune system to discover and destroy cells showing those characteristics.

Molecular biologist Professor Archa Fox from the University of Western Australia said the outcome of the trial was exciting because it offered an alternative to broad and non-specific cancer treatments.

Treating all cancer with mRNA

The Phase II clinical trial of the melanoma treatment involved 157 patients with stage three or stage four melanoma whose tumours had been surgically removed.

It was conducted in Australia and the US targeting patients who were at high risk of their cancer returning, and has not yet been peer-reviewed, or published in a scientific journal.

Moderna and the researchers will now present the results to regulatory authorities with a view to conducting a trial of 1000 patients next year.

Professor Long said research into treating melanoma had driven the development of immunotherapies and was now forging a way to treat cancer with mRNA vaccines.

"It is absolutely a world first, to show you can personalise a cancer vaccine in patients who already have cancer."

Promising research into using mRNA vaccine against cancers. Neat.

And it's in line with the robots' population reduction strategy. What a chance!

I have a better idea. A very robust virus that can infect all computers. Wouldn't it be great? Just like the vaccine. Attenuated computer virus, how about?

I'm the world's stupidest moron

Take your conspiritard angry ranting BS to angry ranting

That is really cool.

That is really cool.

I thought so too. If it could work against many cancers that's quite the scourge we can defeat

Long live science and research

That is really cool.

mRNA vaccines?

Long live science.

If you had stage 4 cancer, you might decide the risk is worth it. Lots of drugs used to treat cancer cause terrible side effects.

If you had stage 4 cancer, you might decide the risk is worth it. Lots of drugs used to treat cancer cause terrible side effects.

How often do you take a vaccine while you have the late stage disease?

The definition of vaccine has changed now. Apparently they work like therapeutics.

When I was young vaccines prevented disease.

I've never been against people trying a medical treatment if that's what they want.

I don't think they should call this a vaccine.

<3

Quote from: Space Cowgirl on December 14, 2022, 04:30:34 PM

If you had stage 4 cancer, you might decide the risk is worth it. Lots of drugs used to treat cancer cause terrible side effects.

How often do you take a vaccine while you have the late stage disease?

The definition of vaccine has changed now. Apparently they work like therapeutics.

When I was young vaccines prevented disease.

I've never been against people trying a medical treatment if that's what they want.

I suggest you read the quote from the link again. Let me know if you continue to have problems understanding

Remember when you were saying that unvaccinated people were begging for the covid vaccine in hospital.

Then you said that vaccines don't work that way. That you need to take a vaccine as a prevention and not a cure?

I remember.

Things change quickly now depending on the season.

Remember when you were saying that unvaccinated people were begging for the covid vaccine in hospital.

Then you said that vaccines don't work that way. That you need to take a vaccine as a prevention and not a cure?

I remember.

Things change quickly now depending on the season.

Again read what the quote from the link says. It's clear you didn't bother. Then you never do.

If you just want to talk shit, take it to AR. I won't respond to any more of your ignorant BS in this thread

Alright good talk.

I don't think they should call this a vaccine.

2013
What is the difference between a preventative and therapeutic vaccine?
Therapeutic vaccines are different than those that are given for disease prevention such as measles, TB, and influenza vaccines. Therapeutic vaccines are used for treatment as they utilize a patient's own immune system to fight an existing disease rather than immunizing for protection against future disease.[/i]

Therapeutic Cancer Vaccines
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim to treat late stage disease by using a patient’s own immune system. The promising results from clinical trials recently led to the approval of the first therapeutic cancer vaccine by the U.S. Food and Drug Administration.

https://www.sciencedirect.com/topics/medicine-and-dentistry/therapeutic-vaccine

Splendid.

Obviously no vaccine will ever be as safe or as effective as the covid mRNA vaccines but I'm sure this "therapeutic vaccine" will still be better than the old vaccines which are nowhere near as safe or effective as the covid mRNA vaccines.

I wouldn't be surprised if they soon claim that mRNA vaccines are helping to solve the global food crisis and curb hunger.

There is no link between cancer and vaccines. Cancer is about the death of cells. The cell that exceeds the renewal number limit dies, you cannot delay it with the vaccine. This is more than bullshit, it's robotically stupid! Only a moronic robot has not a brain can claim this stupidy. All these doctors whose claim it should have been investigated whether they run with blood or electrical cells.

Cancer is caused by immune system failure and mRNA vaccines have been proven to suppress your immune system.

As was said if you have stage four cancer you should be able to try any treatment you want to.

However I think we all know that all vaccines moving forward will be made using the mRNA technology which was such a spectacular failure in regards to covid.

Cancer is caused by immune system failure and mRNA vaccines have been proven to suppress your immune system.

As was said if you have stage four cancer you should be able to try any treatment you want to.

However I think we all know that all vaccines moving forward will be made using the mRNA technology which was such a spectacular failure in regards to covid.

Since the increase in the number of dead cells causes cancer, treatments for the elimination of these cells are possible thanks to the immune system. But what I mean is that the death of cells is irreversible.

In this case, as you mentioned, it is certain that mRNA vaccines will have the opposite effect and increase cancer. It does not affect cell regeneration, but can harm it.

I wouldn't be surprised if they soon claim that mRNA vaccines are helping to solve the global food crisis and curb hunger.

There is no link between cancer and vaccines. Cancer is about the death of cells. The cell that exceeds the renewal number limit dies, you cannot delay it with the vaccine. This is more than bullshit, it's robotically stupid! Only a moronic robot has not a brain can claim this stupidy. All these doctors whose claim it should have been investigated whether they run with blood or electrical cells.

Said from a certified virologist and cancer specialist with decades of clinical study and research? I'm sure all of these cancer researchers have no idea what they are talking about in comparison to the vast knowledge you possess regarding cancer research, vaccines & therapeutics.

They don't have our best interests at heart, Stash.
They just want to make money.

Quote from: wise on December 14, 2022, 08:37:20 PM

I wouldn't be surprised if they soon claim that mRNA vaccines are helping to solve the global food crisis and curb hunger.

There is no link between cancer and vaccines. Cancer is about the death of cells. The cell that exceeds the renewal number limit dies, you cannot delay it with the vaccine. This is more than bullshit, it's robotically stupid! Only a moronic robot has not a brain can claim this stupidy. All these doctors whose claim it should have been investigated whether they run with blood or electrical cells.

Said from a certified virologist and cancer specialist with decades of clinical study and research? I'm sure all of these cancer researchers have no idea what they are talking about in comparison to the vast knowledge you possess regarding cancer research, vaccines & therapeutics.

Doctors who have done decades of studies were discovered that smoking is beneficial to health. I think you missed this post.

Are they sure smoking does cancer or vice versa?

Camel is good for health?


Or is it chesterfied?


No, doctors have found that Philip Morris is the best.


But throat doctors have voted for "Old Gold" is best for our throat.

November 2021.

This will be just like lead, asbestos or cigarettes. By the time you have to admit I'm right it will be too late.

November 2021.

Quote from: disputeone on November 26, 2021, 02:41:50 PM

This will be just like lead, asbestos or cigarettes. By the time you have to admit I'm right it will be too late.

Hmm. Ok.



The truth is clear. Doctors manipulate science according to the payer. If a company that sells cyanide pays them well, we could read thousands of articles about cyanide actually being good for health. And people like Shifter will voluntarily propagate it. It's probably running free with stray electricity.

Alright people.  We're going to lock this thread until we can learn how to discuss science without completely shitting it up with antivaxxer talk.

Good day Sirs.