I am not at all clear on what the "Great Babel" is. Babel is place name mentioned twice in Genesis, where mankind disobeyed God's command to spread out and fill the earth and was forcibly dispersed by having their languages diversified. The Anti-Christ identified in Revelation chapter 13 is clearly Roman or the Roman Empire collectively; it is identifed with the number 666 ... unlike the Greek or Hebrew system, only some of the Latin alphabet was used as numbers: I + V + X + L + C + D = 666 (the letter M, according to Montanus, was not used as a number until medieval times).
Mohammed may have been marginally literate, at least in any language other than Arabic, and clearly heard a good deal of Christian (and maybe Jewish) preaching and much non-canonical Jewish and Christian folklore, even some heretical stories, about biblical characters, and wove this (with either variations or errors in memory - such as confusing Haman with Pharoah) in his scraps which were subsequently collected as the Koran. The Koran itself had some of the sort of textual variants as afflicts the New Testament manuscripts ... until some centuries after Mohammed's death when the Califf Omar ordered one and only one master text established and all other manuscripts destroyed (the interior of dome of the Al-Asqa Mosque in Jerusalem still has, from about the 9th century, some quotations from vanished Koran manuscripts). If you regard the Hebrew Old Testament (and maybe the Greek New Testament) as reliable, then you would regard the Koran as very distorted.
However, Revelations describes a teaching which is a false scripture and a false synagogue and this might be a prediction of Islam.