Just curious, is the ISS in the same general degree of the sky when it flies over any particular area or is it ever lower or higher in the sky? For example, could it ever be seen just above the horizon at a location directly South of one of the locations they have listed on their schedule?
Not quite sure what you're asking, but I'll take a stab at answering anyway.
At a given moment in time, when the ISS is directly over a given location, it would be just on the horizon for someone approximately 2,000km away in any direction. This does not mean it would be visible from 2,000km away, although it might well be, I haven't tried it out to see.
For my example, the 100km difference between my location and the location I get forecasts for would make a maximum difference to the viewing angle of about 15° at the point it passes directly overhead. This is about equivalent to the distance between your index finger and pinky finger with your fingers splayed as far as they go at arms reach. At other points, the difference in viewing angle would be less (would you like a diagram to show why this is?). This is consistent with my experiences of viewing the ISS.